Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 4/20 | 0.61 |
| ▸ | AGTR2 | P50052 | 4/20 | 0.61 |
| ▸ | PPARG | P37231 | 3/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7299732 | 0.99 | AGTR1 (0.60) | AGTR1AGTR2PPARG | |
| SCHEMBL7308943 | 0.91 | AGTR1 (0.62) | AGTR1AGTR2PPARG | |
| SCHEMBL7302811 | 0.90 | AGTR1 (0.49) | AGTR1AGTR2PPARG | |
| SCHEMBL7299289 | 0.89 | AGTR1 (0.67) | AGTR1AGTR2 | |
| SCHEMBL7303220 | 0.89 | AGTR1 (0.61) | AGTR1AGTR2PPARG | |
| Hydrochloric Acid SCHEMBL7299273 | 0.88 | AGTR1 (0.61) | AGTR1AGTR2PPARG | |
| SCHEMBL7303897 | 0.84 | AGTR1 (0.65) | AGTR1AGTR2PPARG | |
| SCHEMBL7303216 | 0.82 | AGTR1 (0.62) | AGTR1AGTR2 | |
| Hydrochloric Acid SCHEMBL7299270 | 0.82 | AGTR1 (0.61) | AGTR1AGTR2 | |
| SCHEMBL8563587 | 0.81 | AGTR1 (0.50) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5646171-A | HYPOTENSIVE AGENTS | SANKYO COMPANY, LIMITED (JP) | 1997-07-08 | — | — | US | disclosed |
| US-5616599-A | HYPOTENSIVE AGENTS FOR CARDIOVASCULAR DISORDER | SANKYO COMPANY, LIMITED (JP) | 1997-04-01 | — | — | US | disclosed |
| EP-0545912-A2 | 1-Biphenylmethylimidazole derivatives, their preparation and their therapeutic use | Sankyo Company Limited (JP) | 1993-06-09 | — | — | EP | disclosed |
| EP-0503785-A1 | 1-Biphenylimidazole derivatives, their preparation and their therapeutic use | Sankyo Company Limited (JP) | 1992-09-16 | — | — | EP | disclosed |