Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGT | P01019 | 2/20 | 0.47 |
| ▸ | AGTR1 | P30556 | 7/20 | 0.46 |
| ▸ | AGTR2 | P50052 | 7/20 | 0.46 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.39 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7301888 | 0.95 | AGTR1 (0.48) | AGTAGTR1AGTR2ABCC3ABCC4 | |
| SCHEMBL7303313 | 0.93 | AGT (0.46) | AGTAGTR1AGTR2 | |
| SCHEMBL7303806 | 0.92 | AGTR1 (0.44) | AGTAGTR1AGTR2ABCC3ABCC4 | |
| SCHEMBL8845361 | 0.92 | AGTR1 (0.43) | AGTAGTR1AGTR2ABCC3ABCC4 | |
| SCHEMBL7312346 | 0.89 | AGT (0.46) | AGTAGTR1AGTR2 | |
| SCHEMBL7310274 | 0.87 | AGT (0.45) | AGTAGTR1AGTR2 | |
| SCHEMBL7304989 | 0.85 | AGTR1 (0.48) | AGTAGTR1AGTR2 | |
| SCHEMBL9203557 | 0.85 | AGTR1 (0.48) | AGTAGTR1AGTR2 | |
| SCHEMBL8845233 | 0.84 | AGTR1 (0.47) | AGTAGTR1AGTR2 | |
| SCHEMBL7312371 | 0.83 | AGTR1 (0.46) | AGTAGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0503785-A1 | 1-Biphenylimidazole derivatives, their preparation and their therapeutic use | Sankyo Company Limited (JP) | 1992-09-16 | — | — | EP | disclosed |