Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 7/20 | 0.47 |
| ▸ | AGTR2 | P50052 | 7/20 | 0.47 |
| ▸ | AGT | P01019 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9203557 | 0.90 | AGTR1 (0.48) | AGTR1AGTR2AGTRAB9A | |
| SCHEMBL7304989 | 0.90 | AGTR1 (0.48) | AGTR1AGTR2AGT | |
| SCHEMBL7301888 | 0.88 | AGTR1 (0.48) | AGTR1AGTR2AGT | |
| SCHEMBL7312371 | 0.88 | AGTR1 (0.46) | AGTR1AGTR2AGTRAB9A | |
| SCHEMBL7312346 | 0.85 | AGT (0.46) | AGTR1AGTR2AGT | |
| SCHEMBL7308714 | 0.84 | AGT (0.47) | AGTR1AGTR2AGT | |
| SCHEMBL7303313 | 0.83 | AGT (0.46) | AGTR1AGTR2AGT | |
| SCHEMBL7310274 | 0.83 | AGT (0.45) | AGTR1AGTR2AGT | |
| SCHEMBL7303806 | 0.82 | AGTR1 (0.44) | AGTR1AGTR2AGTRAB9A | |
| SCHEMBL8845361 | 0.81 | AGTR1 (0.43) | AGTR1AGTR2AGTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5646171-A | HYPOTENSIVE AGENTS | SANKYO COMPANY, LIMITED (JP) | 1997-07-08 | — | — | US | disclosed |
| US-5616599-A | HYPOTENSIVE AGENTS FOR CARDIOVASCULAR DISORDER | SANKYO COMPANY, LIMITED (JP) | 1997-04-01 | — | — | US | disclosed |