Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 11/20 | 0.57 |
| ▸ | MAOA | P21397 | 5/20 | 0.57 |
| ▸ | RXRA | P19793 | 3/20 | 0.48 |
| ▸ | RXRB | P28702 | 3/20 | 0.48 |
| ▸ | RXRG | P48443 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.44 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7305882 | 0.80 | RXRA (0.45) | MAOBMAOARXRARXRBRXRG | |
| SCHEMBL7305943 | 0.77 | MAOB (0.46) | MAOBRAB9AACHENPC1 | |
| SCHEMBL7312304 | 0.70 | PPARA (0.53) | MAOBMAOARXRARXRBRXRG | |
| SCHEMBL7308736 | 0.70 | MAOB (0.51) | MAOBMAOARXRARXRBRXRG | |
| SCHEMBL4429103 | 0.69 | ITGB3 (0.70) | MAOBMAOARXRARXRBRXRG | |
| SCHEMBL29097893 | 0.69 | S1PR1 (0.53) | MAOBMAOARXRARXRBRXRG | |
| SCHEMBL4423694 | 0.68 | ITGB3 (0.76) | MAOBMAOA | |
| SCHEMBL29741480 | 0.68 | MAOB (0.81) | MAOBMAOARAB9ASMPD1 | |
| SCHEMBL18664184 | 0.68 | MAOB (0.81) | MAOBMAOARAB9ASMPD1 | |
| SCHEMBL4419593 | 0.67 | ITGB3 (0.72) | MAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709370-B1 | Bicyclic compounds useful as platelet aggregation inhibitors | MITSUI CHEMICALS INC (JP) | 1999-01-13 | — | — | EP | disclosed |
| US-5629321-A | FIBRINOGEN ANTAGONIST | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0709370-A1 | Bicyclic compounds useful as platelet aggregation inhibitors | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-05-01 | — | — | EP | disclosed |