Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7023419 | 0.78 | ALDH1A1 (0.48) | ALDH1A1HCAR2LMNAHSD17B10MAPT | |
| Methyl Alcohol SCHEMBL11376423 | 0.76 | ALDH1A1 (0.47) | ALDH1A1HCAR2LMNAHSD17B10MAPT | |
| SCHEMBL11506740 | 0.76 | ALDH1A1 (0.38) | ALDH1A1HCAR2LMNAHSD17B10MAPT | |
| SCHEMBL9320930 | 0.76 | ALDH1A1 (0.37) | ALDH1A1HCAR2LMNAHSD17B10MAPT | |
| SCHEMBL2338677 | 0.76 | ALDH1A1 (0.38) | ALDH1A1HCAR2LMNAHSD17B10MAPT | |
| SCHEMBL7186238 | 0.76 | ALDH1A1 (0.38) | ALDH1A1HCAR2LMNAHSD17B10MAPT | |
| SCHEMBL649921 | 0.76 | ALDH1A1 (0.42) | ALDH1A1HCAR2LMNAHSD17B10MAPT | |
| SCHEMBL12003315 | 0.74 | ALDH1A1 (0.36) | ALDH1A1HCAR2LMNAHSD17B10MAPT | |
| SCHEMBL18938327 | 0.74 | ALDH1A1 (0.36) | ALDH1A1HCAR2LMNAHSD17B10MAPT | |
| Acetic Acid SCHEMBL8846281 | 0.74 | ALDH1A1 (0.32) | ALDH1A1HCAR2LMNAHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0703216-B1 | Amidinophenol derivatives as protease inhibitors | ONO PHARMACEUTICAL CO (JP) | 1999-04-07 | — | — | EP | claimed |
| EP-0588655-B1 | Amidinophenol derivatives | ONO PHARMACEUTICAL CO (JP) | 1996-12-04 | — | — | EP | claimed |
| US-5622984-A | INHIBITORS OF PHOSPHOLIPASE, VARIOUS PROTEASES | ONO PHARMACEUTICAL COMPANY, LIMITED (JP) | 1997-04-22 | — | — | US | disclosed |