Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1632527 | 0.81 | ALDH1A1 (0.39) | ALDH1A1HCAR2CA12CA1CA2 | |
| SCHEMBL7023419 | 0.81 | ALDH1A1 (0.48) | ALDH1A1HCAR2LMNAHSD17B10ALOX15 | |
| SCHEMBL23225639 | 0.80 | CA12 (0.35) | ALDH1A1CA12CA1CA2CA9 | |
| SCHEMBL11506740 | 0.79 | ALDH1A1 (0.38) | ALDH1A1HCAR2LMNAHSD17B10ALOX15 | |
| SCHEMBL2338677 | 0.79 | ALDH1A1 (0.38) | ALDH1A1HCAR2LMNAHSD17B10ALOX15 | |
| Methyl Alcohol SCHEMBL11376423 | 0.79 | ALDH1A1 (0.47) | ALDH1A1HCAR2LMNAHSD17B10ALOX15 | |
| SCHEMBL24131731 | 0.79 | TSHR (0.50) | ALDH1A1LMNAGAAMEN1KMT2A | |
| SCHEMBL29144627 | 0.78 | — | — | |
| SCHEMBL10690127 | 0.78 | — | — | |
| SCHEMBL12003315 | 0.78 | ALDH1A1 (0.36) | ALDH1A1HCAR2LMNAHSD17B10ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6583177-B2 | Amidinophenol derivatives as leukotriene B4 (LTB4)antagonists, phospholipase A2 inhibitors, and trypsin inhibitors. | ONO PHARMACEUTICAL CO., LTD. (JP) | 2003-06-24 | — | — | US | disclosed |
| US-20020128315-A1 | Leukotriene B4 antagonist compounds and method for treatment | NAKAI HISAO (JP) | 2002-09-12 | — | — | US | disclosed |
| US-6262114-B1 | NOVEL AMIDINOPHENOL DERIVATIVES; INHIBITORS OF PHOSPHOLIPASE A2 AND/OR TRYPSIN | ONO PHARMACEUTICAL CO., LTD. (JP) | 2001-07-17 | — | — | US | disclosed |
| EP-0703216-B1 | Amidinophenol derivatives as protease inhibitors | ONO PHARMACEUTICAL CO (JP) | 1999-04-07 | — | — | EP | disclosed |
| EP-0703216-A1 | Amidinophenol derivatives as protease inhibitors | ONO PHARMACEUTICAL CO., LTD. (JP) | 1996-03-27 | — | — | EP | disclosed |
| US-4552932-A | Radiation curable polyurethanes | THE B. F. GOODRICH COMPANY (US) | 1985-11-12 | — | — | US | disclosed |
| US-4180505-A | Novel steroidspirooxazolidines and process for their preparation | Richter Gedeon Vegyeszet, Gyar RT (HU) | 1979-12-25 | — | — | US | disclosed |
| US-4100143-A | Filaments which may be cross-linked comprising at least 65% acrylonitrile and 0.5-10% N-methylol derivative of a urethane | BAYER AKTIENGESELLSCHAFT (DE) | 1978-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020128315-A1 | Leukotriene B4 antagonist compounds and method for treatment | LTB4R2, LTB4R, LTA4H | ALDH1A1 1930/4885HCAR2 972/4885CA12 3321/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.