SCHEMBL7308758

SCHEMBL7308758

Cc1c(C(=O)O)ccc(O)c1C(N)=O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CSNK2A1 P68400 1/20 0.46
SELL P14151 1/20 0.45
SELP P16109 1/20 0.45
ALDH1A1 P00352 3/20 0.41
KDM4E B2RXH2 2/20 0.41
CYP3A4 P08684 2/20 0.41
MAPT P10636 2/20 0.41
PTGS2 P35354 2/20 0.41
MEN1 O00255 1/20 0.41
TNF P01375 1/20 0.41
HSPD1 P10809 1/20 0.41
THRB P10828 1/20 0.41
CYP2C9 P11712 1/20 0.41
HPGD P15428 1/20 0.41
ALOX15 P16050 1/20 0.41
CASP1 P29466 1/20 0.41
CYP2C19 P33261 1/20 0.41
KDR P35968 1/20 0.41
BRCA1 P38398 1/20 0.41
RECQL P46063 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1956878 0.88 KDM4E (0.43) CSNK2A1SELLSELPALDH1A1KDM4E
SCHEMBL7147157 0.86 SELL (0.50) CSNK2A1SELLSELPALDH1A1KDM4E
SCHEMBL5224771 0.82 THRB (0.48) CSNK2A1SELLSELPALDH1A1PTGS2
SCHEMBL27726519 0.82 HAAO (0.40) ALDH1A1KDM4EMEN1HPGDKMT2A
SCHEMBL7095311 0.80 SELL (0.59) CSNK2A1SELLSELPALDH1A1KDM4E
SCHEMBL29282585 0.78 AKR1C3 (0.50) CSNK2A1SELLSELPALDH1A1KDM4E
SCHEMBL21408388 0.78 CA12 (0.55) CSNK2A1SELLSELPALDH1A1KDM4E
SCHEMBL30443442 0.77 SELL (0.54) CSNK2A1SELLSELPALDH1A1KDM4E
SCHEMBL317575 0.77 SELL (0.54) CSNK2A1SELLSELPALDH1A1KDM4E
SCHEMBL29625222 0.77 CYP1A2 (0.46) CSNK2A1ALDH1A1KDM4ECYP3A4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4021472-A ANTIPLASMIN AND ANTITRYPSIN ONO PHARMACEUTICAL CO., LTD. (JA) 1977-05-03 US disclosed