SCHEMBL7147157

SCHEMBL7147157

Cc1c(C(=O)O)ccc(O)c1C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SELL P14151 1/20 0.50
SELP P16109 1/20 0.50
CSNK2A1 P68400 1/20 0.50
CA1 P00915 5/20 0.48
CA2 P00918 5/20 0.48
CA12 O43570 4/20 0.48
CA7 P43166 4/20 0.48
CA9 Q16790 4/20 0.48
CA14 Q9ULX7 4/20 0.48
MYC P01106 2/20 0.44
MCL1 Q07820 3/20 0.44
ALDH1A1 P00352 5/20 0.43
PTGS2 P35354 2/20 0.43
ALOX5 P09917 1/20 0.43
TSHR P16473 1/20 0.43
CYP1A2 P05177 1/20 0.42
KLKB1 P03952 1/20 0.42
CTSB P07858 1/20 0.42
ELANE P08246 1/20 0.42
MMP9 P14780 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5224771 0.88 THRB (0.48) SELLSELPCSNK2A1CA1CA2
SCHEMBL7308758 0.86 CSNK2A1 (0.46) SELLSELPCSNK2A1CA1CA2
SCHEMBL1520727 0.84 CA12 (0.54) SELLSELPCSNK2A1CA1CA2
SCHEMBL6334298 0.84 CYP1A2 (0.48) SELLSELPCSNK2A1MYCALDH1A1
SCHEMBL29282585 0.83 AKR1C3 (0.50) SELLSELPCSNK2A1CA1CA2
SCHEMBL21408388 0.83 CA12 (0.55) SELLSELPCSNK2A1CA1CA2
SCHEMBL14059057 0.83 CA12 (0.50) CSNK2A1CA1CA2CA12CA7
SCHEMBL4123194 0.83 SELL (0.50) SELLSELPCSNK2A1CA1CA2
SCHEMBL317575 0.82 SELL (0.54) SELLSELPCSNK2A1CA1CA2
SCHEMBL30443442 0.82 SELL (0.54) SELLSELPCSNK2A1CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2920227-B1 EPOXY RESIN SYSTEM CONTAINING POLYETHYLENE TETRAAMINES FOR RESIN TRANSFER MOLDING PROCESSES DOW GLOBAL TECHNOLOGIES LLC (US) 2017-02-08 EP claimed
US-20230364247-A1 NON-LINEAR MULTIBLOCK COPOLYMER-DRUG CONJUGATES FOR THE DELIVERY OF ACTIVE AGENTS THE JOHNS HOPKINS UNIVERSITY 2023-11-16 US disclosed
US-11660349-B2 Non-linear multiblock copolymer-drug conjugates for the delivery of active agents THE JOHNS HOPKINS UNIVERSITY (US) 2023-05-30 US disclosed
CN-105340034-A Electrolysis solution for electrolytic capacitor, and electrolytic capacitor CARLIT HOLDINGS CO LTD 2016-02-17 CN disclosed
CN-101094827-B Benzene compound having two or more substituents DAIICHI SANKYO CO LTD 2012-06-13 CN disclosed
CN-101094827-A Benzene compound having two or more substituents SANKYO CO (JP) 2007-12-26 CN disclosed
CN-1950085-A 3- (4-heteroarylcyclohexylamino) cyclopentanecarboxamides as chemokine receptor modulators INCYTE CORP (US) 2007-04-18 CN disclosed
US-6525006-B2 Can be used to metal processing such as cutting, grinding and plastic working KYODO YUSHI CO., LTD. (JP) 2003-02-25 US disclosed
US-20020193263-A1 Lubricant composition KYODO YUSHI CO., LTD. (JP) 2002-12-19 US disclosed
US-4628335-A BISHYDROXYCUMYLBENZENE COMPOUND AS COLOR DEVELOPER FUJI PHOTO FILM CO., LTD. (JP) 1986-12-09 US disclosed
US-4590295-A Process for the manufacture of p-hydroxyphenyl-acetic acid HOECHST AKTIENGESELLSCHAFT (DE) 1986-05-20 US disclosed
EP-0032374-B1 PROCESS FOR THE PREPARATION OF P-HYDROXYPHENYLACETIC ACID HOECHST AKTIENGESELLSCHAFT (DE) 1983-03-09 EP disclosed
EP-0032374-A1 Process for the preparation of p-hydroxyphenylacetic acid HOECHST AKTIENGESELLSCHAFT (DE) 1981-07-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11660349-B2 Non-linear multiblock copolymer-drug conjugates for the delivery of active agents VEGFA, UACA, PDE6A SELL 733/4885SELP 274/4885CSNK2A1 2993/4885
US-20230364247-A1 NON-LINEAR MULTIBLOCK COPOLYMER-DRUG CONJUGATES FOR THE DELIVERY OF ACTIVE AGENTS VEGFA, UACA, PDE6A SELL 733/4885SELP 274/4885CSNK2A1 2993/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.