Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 3/20 | 0.31 |
| ▸ | CA1 | P00915 | 3/20 | 0.31 |
| ▸ | CA2 | P00918 | 3/20 | 0.31 |
| ▸ | CA7 | P43166 | 3/20 | 0.31 |
| ▸ | CA9 | Q16790 | 3/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.30 |
| ▸ | RELA | Q04206 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7310457 | 0.68 | — | — | |
| SCHEMBL7308837 | 0.59 | NPSR1 (0.34) | NPSR1ALDH1A1KDM4EL3MBTL1TSHR | |
| SCHEMBL819613 | 0.59 | CHRM3 (0.42) | NPSR1ALDH1A1KDM4EL3MBTL1TSHR | |
| SCHEMBL10937960 | 0.57 | CHRM3 (0.45) | NPSR1ALDH1A1KDM4EL3MBTL1TSHR | |
| SCHEMBL22362537 | 0.57 | TSHR (0.41) | NPSR1ALDH1A1KDM4EL3MBTL1TSHR | |
| SCHEMBL10639650 | 0.57 | TSHR (0.41) | NPSR1ALDH1A1KDM4EL3MBTL1TSHR | |
| SCHEMBL6850637 | 0.56 | SETD7 (0.51) | NPSR1ALDH1A1KDM4EL3MBTL1PKM | |
| SCHEMBL9034755 | 0.55 | MAPK1 (0.48) | NPSR1ALDH1A1KDM4ESMN1; SMN2MAPT | |
| SCHEMBL10260335 | 0.53 | CA1 (0.57) | NPSR1ALDH1A1KDM4ESMN1; SMN2L3MBTL1 | |
| SCHEMBL19387238 | 0.53 | CA1 (0.70) | ALDH1A1KDM4EL3MBTL1TSHRCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5596012-A | Saccharin derivatives useful as proteolytic enzyme inhibitors and compositions and method of use thereof | STERLING WINTHROP INC. (US) | 1997-01-21 | — | — | US | claimed |
| US-5371074-A | Use of saccharin derivatives as proteolytic enzyme inhibitors | STERLING WINTHROP INC. (US) | 1994-12-06 | — | — | US | claimed |
| EP-0542372-A1 | 2-Substituted saccharin derivative proteolytic enzyme inhibitors | STERLING WINTHROP INC. (US) | 1993-05-19 | — | — | EP | claimed |