Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 6/20 | 0.43 |
| ▸ | CTSL | P07711 | 3/20 | 0.37 |
| ▸ | PSMB11 | A5LHX3 | 2/20 | 0.36 |
| ▸ | PSMA7 | O14818 | 2/20 | 0.36 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.36 |
| ▸ | PSMA1 | P25786 | 2/20 | 0.36 |
| ▸ | PSMA2 | P25787 | 2/20 | 0.36 |
| ▸ | PSMA3 | P25788 | 2/20 | 0.36 |
| ▸ | PSMA4 | P25789 | 2/20 | 0.36 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.36 |
| ▸ | PSMB9 | P28065 | 2/20 | 0.36 |
| ▸ | PSMA5 | P28066 | 2/20 | 0.36 |
| ▸ | PSMB4 | P28070 | 2/20 | 0.36 |
| ▸ | PSMB6 | P28072 | 2/20 | 0.36 |
| ▸ | PSMB10 | P40306 | 2/20 | 0.36 |
| ▸ | PSMB3 | P49720 | 2/20 | 0.36 |
| ▸ | PSMB2 | P49721 | 2/20 | 0.36 |
| ▸ | PSMA6 | P60900 | 2/20 | 0.36 |
| ▸ | PSMA8 | Q8TAA3 | 2/20 | 0.36 |
| ▸ | PSMB7 | Q99436 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8888482 | 1.00 | PSMB5 (0.43) | PSMB5CTSLPSMB11PSMA7PSMB1 | |
| SCHEMBL7311641 | 0.94 | PSMB5 (0.43) | PSMB5CTSLALDH1A1HPGDMMP3 | |
| SCHEMBL7311652 | 0.94 | PSMB5 (0.43) | PSMB5CTSLALDH1A1HPGDMMP3 | |
| SCHEMBL7311337 | 0.91 | POLB (0.41) | PSMB5CTSLALDH1A1HPGDMMP3 | |
| SCHEMBL7311345 | 0.91 | POLB (0.41) | PSMB5CTSLALDH1A1HPGDMMP3 | |
| SCHEMBL7311324 | 0.90 | ALDH1A1 (0.36) | PSMB5CTSLALDH1A1HPGDMMP3 | |
| SCHEMBL7311308 | 0.90 | ALDH1A1 (0.36) | PSMB5CTSLALDH1A1HPGDMMP3 | |
| SCHEMBL7306104 | 0.89 | ALDH1A1 (0.35) | PSMB5CTSLALDH1A1HPGDMMP3 | |
| SCHEMBL7306122 | 0.89 | ALDH1A1 (0.35) | PSMB5CTSLALDH1A1HPGDMMP3 | |
| SCHEMBL7313606 | 0.89 | CTSL (0.44) | CTSLALDH1A1HPGDUSP2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0525420-B1 | Pseudopeptides and dipeptides characterised by a substituted methyl ketone moiety at the C-terminus as thiol protease inhibitors | MITSUBISHI CHEM CORP (JP) | 1999-05-12 | — | — | EP | disclosed |
| US-5834508-A | PROTEASE ENZYME INHIBITORS; MUSCLE DISORDERS | MITSUBISHI CHEMICAL CORPORATION (JP) | 1998-11-10 | — | — | US | disclosed |
| US-5639783-A | POTENT PROTEASE INHIBITOR FOR TREATING MUSCULAR, NERVOUS SYSTEM DISEASES | MITSUBISHI CHEMICAL CORPORATION (JP) | 1997-06-17 | — | — | US | disclosed |
| EP-0525420-A1 | Pseudopeptides and dipeptides characterised by a substituted methyl ketone moiety at the C-terminus as thiol protease inhibitors | Mitsubishi Chemical Corporation (JP) | 1993-02-03 | — | — | EP | disclosed |