Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7309469 | 0.95 | AGTR2 (0.39) | AGTR2EDNRA | |
| SCHEMBL7310871 | 0.94 | AGTR2 (0.37) | AGTR2 | |
| SCHEMBL7306339 | 0.94 | AGTR2 (0.36) | AGTR2 | |
| SCHEMBL7305207 | 0.93 | AGTR2 (0.36) | AGTR2 | |
| SCHEMBL9429620 | 0.91 | AGTR2 (0.35) | AGTR2 | |
| SCHEMBL7302787 | 0.90 | AGTR2 (0.39) | AGTR2 | |
| SCHEMBL7312882 | 0.90 | AGTR2 (0.40) | AGTR2 | |
| SCHEMBL7306526 | 0.89 | AGTR2 (0.39) | AGTR2EDNRA | |
| SCHEMBL7302537 | 0.89 | AGTR2 (0.44) | AGTR2 | |
| SCHEMBL7308626 | 0.88 | AGTR2 (0.39) | AGTR2EDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5310927-A | Hypotensive agents; cognition activators; imidazolyl-2-aryl derivatives | GLAXO GROUP LIMITED (GB) | 1994-05-10 | — | — | US | disclosed |
| EP-0514193-A1 | N-linked imidazolyl-methyl benzofuran derivatives with antihypotensive activity | GLAXO GROUP LIMITED (GB) | 1992-11-19 | — | — | EP | disclosed |