Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 1/20 | 0.35 |
| ▸ | CFTR | P13569 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | P2RY12 | Q9H244 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7310871 | 0.93 | AGTR2 (0.37) | AGTR2 | |
| SCHEMBL7308926 | 0.91 | AGTR2 (0.36) | AGTR2 | |
| SCHEMBL7305207 | 0.91 | AGTR2 (0.36) | AGTR2 | |
| SCHEMBL7306339 | 0.91 | AGTR2 (0.36) | AGTR2 | |
| SCHEMBL9429570 | 0.89 | ALDH1A1 (0.38) | AGTR2TSHRALDH1A1 | |
| SCHEMBL7312882 | 0.88 | AGTR2 (0.40) | AGTR2 | |
| SCHEMBL7302787 | 0.87 | AGTR2 (0.39) | AGTR2 | |
| SCHEMBL7309469 | 0.87 | AGTR2 (0.39) | AGTR2 | |
| SCHEMBL7308626 | 0.87 | AGTR2 (0.39) | AGTR2 | |
| SCHEMBL9429517 | 0.85 | ALDH1A1 (0.36) | TSHRALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5310927-A | Hypotensive agents; cognition activators; imidazolyl-2-aryl derivatives | GLAXO GROUP LIMITED (GB) | 1994-05-10 | — | — | US | disclosed |