Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | ADRB2 | P07550 | 10/20 | 0.64 |
| ▸ | ADRB1 | P08588 | 9/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.63 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.63 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.63 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.63 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.63 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.63 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.63 |
| ▸ | ADRB3 | P13945 | 8/20 | 0.62 |
| ▸ | OXTR | P30559 | 1/20 | 0.62 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9700731 | 0.87 | ADRB2 (0.66) | KMT2AADRB2ADRB1LMNASLC6A4 | |
| SCHEMBL9700569 | 0.87 | ADRB2 (0.66) | KMT2AADRB2ADRB1LMNASLC6A4 | |
| SCHEMBL11202332 | 0.86 | ADRB2 (0.64) | KMT2AADRB2ADRB1LMNASLC6A4 | |
| SCHEMBL11429165 | 0.86 | ADRB2 (0.65) | KMT2AADRB2ADRB1LMNASLC6A4 | |
| SCHEMBL2919063 | 0.86 | KMT2A (0.59) | KMT2AADRB2ADRB1LMNAALDH1A1 | |
| Sulfuric Acid SCHEMBL10570655 | 0.82 | ADRB3 (0.62) | KMT2AADRB2ADRB1LMNASLC6A4 | |
| SCHEMBL1970148 | 0.81 | ADRB2 (0.64) | KMT2AADRB2ADRB1LMNASLC6A4 | |
| SCHEMBL7435099 | 0.80 | ATM (0.76) | KMT2AADRB2ALDH1A1KDM4EMEN1 | |
| SCHEMBL11884643 | 0.80 | ADRB2 (0.80) | KMT2AADRB2ADRB1SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL9781659 | 0.80 | ADRB2 (0.63) | KMT2AADRB2ADRB1LMNASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4258062-A | ISOPRENALINE ANTAGONISTS EFFECTING HEART RATE AND BLOOD PRESSURE | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1981-03-24 | — | — | US | disclosed |
| US-4171370-A | Phenoxy-amino-propanols | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1979-10-16 | — | — | US | disclosed |