Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 14/20 | 0.62 |
| ▸ | ITGA2B | P08514 | 14/20 | 0.62 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.37 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7305419 | 0.90 | ITGB3 (0.74) | ITGB3ITGA2BDGAT1 | |
| SCHEMBL7305638 | 0.87 | ITGB3 (0.55) | ITGB3ITGA2BDGAT1NPC1CYP1A2 | |
| SCHEMBL7300021 | 0.84 | ITGB3 (0.86) | ITGB3ITGA2BDGAT1MCHR1 | |
| SCHEMBL7306072 | 0.83 | ITGB3 (0.77) | ITGB3ITGA2BDGAT1MCHR1 | |
| SCHEMBL7305023 | 0.83 | ITGB3 (0.71) | ITGB3ITGA2BDGAT1NPC1RAB9A | |
| SCHEMBL7307011 | 0.83 | ITGB3 (0.62) | ITGB3ITGA2BDGAT1MCHR1 | |
| SCHEMBL7297297 | 0.81 | ITGB3 (0.55) | ITGB3ITGA2BDGAT1MCHR1 | |
| SCHEMBL7299162 | 0.78 | ITGB3 (0.61) | ITGB3ITGA2BDGAT1MCHR1 | |
| SCHEMBL7309674 | 0.78 | ITGB3 (0.61) | ITGB3ITGA2BDGAT1MCHR1 | |
| SCHEMBL7298489 | 0.77 | ITGB3 (1.00) | ITGB3ITGA2BMCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709370-B1 | Bicyclic compounds useful as platelet aggregation inhibitors | MITSUI CHEMICALS INC (JP) | 1999-01-13 | — | — | EP | disclosed |
| US-5629321-A | FIBRINOGEN ANTAGONIST | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0709370-A1 | Bicyclic compounds useful as platelet aggregation inhibitors | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-05-01 | — | — | EP | disclosed |