Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 12/20 | 0.71 |
| ▸ | ITGA2B | P08514 | 12/20 | 0.71 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.47 |
| ▸ | RXRA | P19793 | 3/20 | 0.46 |
| ▸ | RXRB | P28702 | 3/20 | 0.46 |
| ▸ | RXRG | P48443 | 3/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7307011 | 0.94 | ITGB3 (0.62) | ITGB3ITGA2BDGAT1RXRARXRB | |
| SCHEMBL7300961 | 0.87 | ITGB3 (0.92) | ITGB3ITGA2BRXRARXRBRXRG | |
| SCHEMBL7303640 | 0.84 | ITGB3 (0.70) | ITGB3ITGA2BRXRARXRBRXRG | |
| SCHEMBL7309002 | 0.83 | ITGB3 (0.62) | ITGB3ITGA2BDGAT1NPC1RAB9A | |
| SCHEMBL7302761 | 0.83 | ITGB3 (0.58) | ITGB3ITGA2BFFAR1NPC1RAB9A | |
| SCHEMBL7308788 | 0.81 | ITGB3 (0.81) | ITGB3ITGA2BRXRB | |
| SCHEMBL7306072 | 0.81 | ITGB3 (0.77) | ITGB3ITGA2BDGAT1 | |
| SCHEMBL7300021 | 0.80 | ITGB3 (0.86) | ITGB3ITGA2BDGAT1 | |
| SCHEMBL7297297 | 0.79 | ITGB3 (0.55) | ITGB3ITGA2BDGAT1RXRARXRB | |
| SCHEMBL7307064 | 0.78 | ITGB3 (0.74) | ITGB3ITGA2BRXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709370-B1 | Bicyclic compounds useful as platelet aggregation inhibitors | MITSUI CHEMICALS INC (JP) | 1999-01-13 | — | — | EP | disclosed |
| US-5629321-A | FIBRINOGEN ANTAGONIST | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0709370-A1 | Bicyclic compounds useful as platelet aggregation inhibitors | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-05-01 | — | — | EP | disclosed |