Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 1.00 |
| ▸ | POLB | P06746 | 4/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | TACR3 | P29371 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.59 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.56 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.56 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.56 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27547326 | 0.88 | L3MBTL1 (0.79) | L3MBTL1POLBALDH1A1KDM4ETACR3 | |
| SCHEMBL13629928 | 0.87 | L3MBTL1 (0.77) | L3MBTL1POLBALDH1A1KDM4ETACR3 | |
| SCHEMBL13701287 | 0.86 | L3MBTL1 (0.75) | L3MBTL1POLBALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL6210602 | 0.86 | L3MBTL1 (0.75) | L3MBTL1POLBALDH1A1KDM4ETACR3 | |
| SCHEMBL24663632 | 0.84 | L3MBTL1 (0.73) | L3MBTL1POLBALDH1A1KDM4ETACR3 | |
| SCHEMBL27559589 | 0.84 | L3MBTL1 (0.73) | L3MBTL1POLBALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL1221986 | 0.84 | POLB (1.00) | L3MBTL1POLBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10722408 | 0.84 | HSD11B1 (0.77) | L3MBTL1ALDH1A1KDM4ESMN1; SMN2MAPT | |
| SCHEMBL3967794 | 0.84 | HSD11B1 (0.77) | L3MBTL1ALDH1A1KDM4ESMN1; SMN2MAPT | |
| SCHEMBL15014500 | 0.83 | L3MBTL1 (0.71) | L3MBTL1POLBALDH1A1KDM4ETACR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520336-A2 | Aldehyde derivatives and their use as calpain inhibitors | FUJIREBIO Inc. (JP) | 1992-12-30 | — | — | EP | disclosed |