Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.35 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7306725 | 0.85 | ALDH1A1 (0.40) | ALDH1A1MEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL7306817 | 0.83 | ALDH1A1 (0.39) | ALDH1A1MEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL7319123 | 0.83 | HPGD (0.39) | ALDH1A1KMT2ASMN1; SMN2HPGDMAPT | |
| SCHEMBL10375845 | 0.83 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2AKDM4ESMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7317619 | 0.82 | HPGD (0.39) | ALDH1A1KMT2ASMN1; SMN2HPGDMAPT | |
| SCHEMBL10376583 | 0.82 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL7317613 | 0.81 | PTPN7 (0.32) | ALDH1A1SMN1; SMN2HPGDMAPTTHRB | |
| SCHEMBL7312705 | 0.81 | TNF (0.39) | ALDH1A1KMT2AKDM4ESMN1; SMN2HPGD | |
| SCHEMBL7314929 | 0.80 | FFAR4 (0.38) | ALDH1A1KMT2ASMN1; SMN2HPGDMAPT | |
| SCHEMBL10376006 | 0.80 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2AKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |