Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7309039 | 0.85 | ALDH1A1 (0.40) | ALDH1A1MEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL7306817 | 0.84 | ALDH1A1 (0.39) | ALDH1A1MEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL7306731 | 0.80 | ALDH1A1 (0.38) | ALDH1A1MEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL7314387 | 0.78 | PDE3B (0.42) | ALDH1A1SMN1; SMN2POLBTHRANPC1 | |
| SCHEMBL7313370 | 0.77 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL10377117 | 0.75 | PDE3B (0.42) | ALDH1A1MEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL7313090 | 0.73 | CNR1 (0.42) | ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL10375845 | 0.71 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL10376583 | 0.71 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL7312020 | 0.71 | LMNA (0.46) | ALDH1A1KMT2ASMN1; SMN2THRANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |