Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 18/20 | 0.81 |
| ▸ | F2 | P00734 | 5/20 | 0.81 |
| ▸ | KLK1 | P06870 | 5/20 | 0.81 |
| ▸ | TMPRSS15 | P98073 | 13/20 | 0.43 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7189652 | 0.93 | PRSS1 (0.88) | PRSS1F2KLK1TMPRSS15 | |
| SCHEMBL7189654 | 0.93 | PRSS1 (0.88) | PRSS1F2KLK1TMPRSS15 | |
| SCHEMBL7304805 | 0.90 | PRSS1 (0.70) | PRSS1F2KLK1TMPRSS15 | |
| SCHEMBL1650235 | 0.90 | PRSS1 (1.00) | PRSS1F2KLK1TMPRSS15FTO | |
| SCHEMBL5574445 | 0.89 | PRSS1 (1.00) | PRSS1F2KLK1TMPRSS15FTO | |
| SCHEMBL5569896 | 0.89 | PRSS1 (1.00) | PRSS1F2KLK1TMPRSS15FTO | |
| SCHEMBL7309075 | 0.89 | PRSS1 (1.00) | PRSS1F2KLK1TMPRSS15FTO | |
| SCHEMBL3245051 | 0.88 | PRSS1 (1.00) | PRSS1F2KLK1TMPRSS15 | |
| SCHEMBL7311244 | 0.88 | PRSS1 (1.00) | PRSS1F2KLK1TMPRSS15 | |
| SCHEMBL7191629 | 0.87 | PRSS1 (0.85) | PRSS1F2KLK1TMPRSS15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5614555-A | Amidinophenol derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1997-03-25 | — | — | US | disclosed |
| EP-0588655-B1 | Amidinophenol derivatives | ONO PHARMACEUTICAL CO (JP) | 1996-12-04 | — | — | EP | disclosed |
| EP-0588655-A1 | Amidinophenol derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-03-23 | — | — | EP | disclosed |