Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | VDR | P11473 | 1/20 | 0.37 |
| ▸ | MAN2B1 | O00754 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 7/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | FNTA | P49354 | 1/20 | 0.35 |
| ▸ | FNTB | P49356 | 1/20 | 0.35 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7309103 | 1.00 | MEN1 (0.40) | MEN1GAAKMT2AACETDP1 | |
| SCHEMBL7344084 | 0.91 | PLA2G10 (0.39) | MEN1GAAKMT2ATDP1ROCK2 | |
| Oxalic Acid SCHEMBL7286374 | 0.91 | MEN1 (0.38) | MEN1GAAKMT2AACETDP1 | |
| Oxalic Acid SCHEMBL7287762 | 0.91 | MEN1 (0.38) | MEN1GAAKMT2AACETDP1 | |
| Oxalic Acid SCHEMBL7286295 | 0.88 | CHRM2 (0.39) | MEN1GAAKMT2AACETDP1 | |
| Oxalic Acid SCHEMBL7286271 | 0.88 | CHRM2 (0.39) | MEN1GAAKMT2AACETDP1 | |
| SCHEMBL13354866 | 0.85 | PKM (0.52) | GAAKMT2AROCK2SIGMAR1DRD2 | |
| Oxalic Acid SCHEMBL7285969 | 0.84 | PLA2G10 (0.38) | MEN1GAAKMT2ATDP1ROCK2 | |
| Oxalic Acid SCHEMBL7285955 | 0.84 | PLA2G10 (0.38) | MEN1GAAKMT2ATDP1ROCK2 | |
| SCHEMBL8550139 | 0.79 | HTT (0.50) | GAAACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0950658-A1 | 2-Pipirazinone-1-acetic acid dihydrochloride derivative used to inhibit platelet aggregation | Takeda Chemical Industries, Ltd. (JP) | 1999-10-20 | — | — | EP | disclosed |