Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | ACE | P12821 | 2/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | TDO2 | P48775 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.43 |
| ▸ | ITGAV | P06756 | 3/20 | 0.43 |
| ▸ | TGM2 | P21980 | 1/20 | 0.43 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.43 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.43 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5995725 | 0.89 | GAA (0.48) | HTTGAAPKMKEAP1NFE2L2 | |
| SCHEMBL19474290 | 0.82 | GAA (0.45) | HTTGAAKEAP1NFE2L2IDO1 | |
| SCHEMBL7309092 | 0.79 | MEN1 (0.40) | GAAACE | |
| SCHEMBL7309103 | 0.79 | MEN1 (0.40) | GAAACE | |
| Hydrochloric Acid SCHEMBL7287900 | 0.79 | GLA (0.59) | GAAPKMACESMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7287909 | 0.79 | GLA (0.59) | GAAPKMACESMN1; SMN2 | |
| SCHEMBL13220374 | 0.78 | HTT (0.46) | HTTGAAACEKEAP1NFE2L2 | |
| SCHEMBL13354866 | 0.78 | PKM (0.52) | GAAPKMIDO1 | |
| SCHEMBL8553717 | 0.78 | ITGB3 (0.51) | HTTITGB3 | |
| Hydrochloric Acid SCHEMBL7284411 | 0.76 | GLA (0.49) | GAAPKMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0822931-A1 | PIPERAZINONES USEFUL AS INHIBITORS OF PLATELET AGGREGATION | Takeda Chemical Industries, Ltd. (JP) | 1998-02-11 | — | — | EP | disclosed |