Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 7/20 | 0.52 |
| ▸ | CA9 | Q16790 | 6/20 | 0.52 |
| ▸ | CA1 | P00915 | 4/20 | 0.52 |
| ▸ | CA4 | P22748 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 7/20 | 0.51 |
| ▸ | MAOA | P21397 | 5/20 | 0.51 |
| ▸ | ACHE | P22303 | 2/20 | 0.51 |
| ▸ | AR | P10275 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA7 | P43166 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | CA3 | P07451 | 1/20 | 0.48 |
| ▸ | CA6 | P23280 | 1/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | RXRA | P19793 | 1/20 | 0.46 |
| ▸ | RXRB | P28702 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5617763 | 0.84 | NPC1 (0.74) | CA12CA9CA1CA4NPC1 | |
| SCHEMBL7315339 | 0.82 | MAOB (0.69) | CA12CA9CA1CA4NPC1 | |
| SCHEMBL5617809 | 0.79 | MAOB (0.68) | CA12CA1CA4NPC1RAB9A | |
| SCHEMBL2806115 | 0.77 | ALOX5 (0.69) | NPC1RAB9AMAOBMAOAACHE | |
| SCHEMBL9612911 | 0.75 | CA12 (0.66) | CA12CA9CA1CA4RAB9A | |
| SCHEMBL28373047 | 0.75 | SLC16A3 (0.75) | CA12CA1CA4MAOBMAOA | |
| SCHEMBL12279053 | 0.74 | RXRA (0.72) | NPC1RAB9AMAOBMAOAACHE | |
| SCHEMBL13160063 | 0.74 | RXRA (0.72) | NPC1RAB9AMAOBMAOAACHE | |
| SCHEMBL5618032 | 0.72 | MAOB (0.77) | MAOBMAOAACHEAR | |
| SCHEMBL5617810 | 0.71 | NPC1 (0.76) | CA12CA1CA4NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5414006-A | Monoamine oxidase inhibitors | BASF AKTIENGESELLSCHAFT (DE) | 1995-05-09 | — | — | US | disclosed |
| EP-0594036-A1 | Arylalkyloxythiocoumarines, process for their preparation and therapeutical agents containing them | BASF Aktiengesellschaft (DE) | 1994-04-27 | — | — | EP | disclosed |