Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 12/20 | 0.57 |
| ▸ | ADRB1 | P08588 | 8/20 | 0.57 |
| ▸ | ADRB3 | P13945 | 6/20 | 0.57 |
| ▸ | HTR1A | P08908 | 1/20 | 0.55 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.55 |
| ▸ | HTR2B | P41595 | 1/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7315388 | 0.91 | ADRB2 (0.58) | ADRB2ADRB1ADRB3HTR1AADRA2C | |
| SCHEMBL7311212 | 0.89 | ADRB2 (0.60) | ADRB2ADRB1ADRB3HTR1AADRA2C | |
| SCHEMBL7309393 | 0.89 | ADRB2 (0.54) | ADRB2ADRB1ADRB3HTR1AADRA2C | |
| SCHEMBL7319039 | 0.88 | ADRB2 (0.54) | ADRB2ADRB1ADRB3HTR1AADRA2C | |
| SCHEMBL7314684 | 0.85 | ADRB2 (0.56) | ADRB2ADRB1ADRB3HTR1AADRA2C | |
| SCHEMBL7317896 | 0.84 | ADRB2 (0.56) | ADRB2ADRB1ADRB3HTR1AADRA2C | |
| SCHEMBL7307959 | 0.84 | ADRB2 (0.56) | ADRB2ADRB1ADRB3HTR1AADRA2C | |
| SCHEMBL7305119 | 0.81 | KMT2A (0.50) | ADRB2ADRB1ADRB3HTR1AADRA2C | |
| Fumaric Acid SCHEMBL7310602 | 0.80 | ADRB2 (0.56) | ADRB2ADRB1ADRB3HTR1AADRA2C | |
| Fumaric Acid SCHEMBL7310590 | 0.80 | ADRB2 (0.56) | ADRB2ADRB1ADRB3HTR1AADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4258062-A | ISOPRENALINE ANTAGONISTS EFFECTING HEART RATE AND BLOOD PRESSURE | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1981-03-24 | — | — | US | disclosed |
| US-4171370-A | Phenoxy-amino-propanols | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1979-10-16 | — | — | US | disclosed |