Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 13/20 | 0.54 |
| ▸ | ADRB1 | P08588 | 7/20 | 0.54 |
| ▸ | ADRB3 | P13945 | 6/20 | 0.54 |
| ▸ | HTR1A | P08908 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.47 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.47 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.47 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.47 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7312955 | 0.89 | ADRB2 (0.57) | ADRB2ADRB1ADRB3HTR1AMEN1 | |
| SCHEMBL7309404 | 0.88 | ADRB2 (0.57) | ADRB2ADRB1ADRB3HTR1AMEN1 | |
| SCHEMBL7311038 | 0.88 | ADRB2 (0.56) | ADRB2ADRB1ADRB3HTR1AMEN1 | |
| SCHEMBL7319028 | 0.86 | ADRB2 (0.56) | ADRB2ADRB1ADRB3HTR1AMEN1 | |
| SCHEMBL7318237 | 0.85 | CASR (0.56) | ADRB2ADRB3HTR1AMEN1KMT2A | |
| SCHEMBL7312078 | 0.83 | ADRB2 (0.62) | ADRB2ADRB1ADRB3HTR1ALMNA | |
| SCHEMBL7315445 | 0.82 | ADRB3 (0.56) | ADRB2ADRB1ADRB3MEN1KMT2A | |
| SCHEMBL7306021 | 0.82 | ADRB2 (0.54) | ADRB2ADRB1ADRB3HTR1AMEN1 | |
| SCHEMBL7311030 | 0.82 | ADRB3 (0.55) | ADRB2ADRB1ADRB3HTR1AMEN1 | |
| SCHEMBL7314435 | 0.82 | ADRB3 (0.55) | ADRB2ADRB1ADRB3HTR1AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4258062-A | ISOPRENALINE ANTAGONISTS EFFECTING HEART RATE AND BLOOD PRESSURE | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1981-03-24 | — | — | US | disclosed |
| US-4171370-A | Phenoxy-amino-propanols | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1979-10-16 | — | — | US | disclosed |