Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 9/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | RAF1 | P04049 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL730952 | 1.00 | VCAM1 (0.43) | VCAM1ALDH1A1SMN1; SMN2THRBMAPT | |
| SCHEMBL732931 | 0.80 | NPC1 (0.36) | ALDH1A1SMN1; SMN2HPGDLMNAMAPK1 | |
| SCHEMBL730106 | 0.78 | VCAM1 (0.48) | VCAM1ALDH1A1SMN1; SMN2THRBMAPT | |
| SCHEMBL730105 | 0.78 | VCAM1 (0.48) | VCAM1ALDH1A1SMN1; SMN2THRBMAPT | |
| SCHEMBL6821981 | 0.74 | VCAM1 (0.53) | VCAM1ALDH1A1SMN1; SMN2MAPTHPGD | |
| SCHEMBL7101466 | 0.73 | VCAM1 (0.48) | VCAM1ALDH1A1SMN1; SMN2THRBMAPT | |
| SCHEMBL4442360 | 0.72 | VCAM1 (0.50) | VCAM1ALDH1A1SMN1; SMN2MAPTHPGD | |
| SCHEMBL4442362 | 0.72 | VCAM1 (0.50) | VCAM1ALDH1A1SMN1; SMN2MAPTHPGD | |
| SCHEMBL4442693 | 0.72 | VCAM1 (0.50) | VCAM1ALDH1A1SMN1; SMN2MAPTHPGD | |
| SCHEMBL11625311 | 0.72 | ALDH1A1 (0.48) | VCAM1ALDH1A1SMN1; SMN2MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138335-B2 | Carboxylic acid compounds and medicinal compositions containing the same as the active ingredient | ONO PHARMACEUTICAL CO., LTD (JP) | 2012-03-20 | — | — | US | disclosed |
| US-20100029631-A1 | CARBOXYLIC ACID COMPOUNDS AND MEDICINAL COMPOSITIONS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2010-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029631-A1 | CARBOXYLIC ACID COMPOUNDS AND MEDICINAL COMPOSITIONS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | GPR17, CYSLTR1, KIT | VCAM1 94/4885ALDH1A1 368/4885SMN1; SMN2 3630/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.