Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.65 |
| ▸ | HPGD | P15428 | 6/20 | 0.65 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.62 |
| ▸ | NPC1 | O15118 | 3/20 | 0.62 |
| ▸ | RAB9A | P51151 | 3/20 | 0.62 |
| ▸ | MAOB | P27338 | 5/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | MAOA | P21397 | 4/20 | 0.56 |
| ▸ | BCHE | P06276 | 3/20 | 0.56 |
| ▸ | ACHE | P22303 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23728132 | 1.00 | KDM4E (0.65) | KDM4EALDH1A1HPGDTRPV1NPC1 | |
| SCHEMBL7309566 | 0.82 | KDM4E (0.80) | KDM4EALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL7309562 | 0.82 | KDM4E (0.80) | KDM4EALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL27183471 | 0.81 | ALDH1A1 (0.97) | KDM4EALDH1A1HPGDTRPV1NPC1 | |
| Cinoctramide SCHEMBL2111109 | 0.81 | ALDH1A1 (0.97) | KDM4EALDH1A1HPGDTRPV1NPC1 | |
| SCHEMBL28945273 | 0.81 | HPGD (0.61) | KDM4EALDH1A1HPGDTRPV1NPC1 | |
| SCHEMBL28945275 | 0.81 | HPGD (0.61) | KDM4EALDH1A1HPGDTRPV1NPC1 | |
| SCHEMBL15681754 | 0.80 | NPC1 (0.61) | KDM4EALDH1A1HPGDTRPV1NPC1 | |
| SCHEMBL15884182 | 0.79 | ALDH1A1 (0.78) | KDM4EALDH1A1HPGDTRPV1MAOB | |
| Pyrrolidine SCHEMBL22397855 | 0.79 | KDM4E (0.70) | KDM4EALDH1A1HPGDNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4100034-A1 | COMPOSITIONS COMPRISING EXTRACTS OF APLINIA AND OTHER PLANTS FOR IMPROVING JOINT HEALTH AND TREATING ARTHRITIS | Unigen, Inc. (US) | 2022-12-14 | — | — | EP | disclosed |
| US-20220000964-A1 | Compositions and Methods for Regulating Homeostasis of Chondrocytes, Extracellular Matrix, Articular Cartilage, and Phenotype of Arthritis | UNIGEN, INC. (US) | 2022-01-06 | — | — | US | disclosed |
| WO-2021159042-A1 | COMPOSITIONS COMPRISING EXTRACTS OF APLINIA AND OTHER PLANTS FOR IMPROVING JOINT HEALTH AND TREATING ARTHRITIS | UNIGEN, INC. (US) | 2021-08-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220000964-A1 | Compositions and Methods for Regulating Homeostasis of Chondrocytes, Extracellular Matrix, Articular Cartilage, and Phenotype of Arthritis | COL2A1, COL1A1, CKAP4 | KDM4E 726/4885ALDH1A1 1095/4885HPGD 1993/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.