Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 7/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.39 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.39 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.39 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11980475 | 0.89 | EPHX2 (0.35) | EPHX2EPHX1ITGB3ITGA2BGNAI3 | |
| SCHEMBL3122925 | 0.89 | EPHX2 (0.41) | EPHX2EPHX1GNAI3GNAO1GNAI1 | |
| SCHEMBL27551163 | 0.83 | ITGB3 (0.43) | ITGB3ITGA2BGNAI3GNAO1GNAI1 | |
| SCHEMBL12561511 | 0.83 | POLB (0.51) | EPHX2EPHX1ITGB3ITGA2BGNAI3 | |
| SCHEMBL7299175 | 0.83 | AKR1C3 (0.45) | EPHX2EPHX1ITGB3ITGA2BGNAI3 | |
| SCHEMBL3457863 | 0.81 | EPHX2 (0.39) | EPHX2EPHX1ITGB3ITGA2BGNAI3 | |
| SCHEMBL13597080 | 0.81 | GNAI3 (0.53) | ITGB3ITGA2BGNAI3GNAO1GNAI1 | |
| SCHEMBL26263461 | 0.81 | GNAI3 (0.53) | EPHX2EPHX1ITGB3ITGA2BGNAI3 | |
| SCHEMBL12747180 | 0.80 | EPHX2 (0.43) | EPHX2EPHX1CYP1A2TDP1 | |
| SCHEMBL5013505 | 0.80 | ITGB3 (0.41) | EPHX2EPHX1ITGB3ITGA2BGNAI3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0479601-B1 | Piperidine derivatives and their use as antiarrhythmic agents | AJINOMOTO KK (JP) | 1999-12-15 | — | — | EP | disclosed |
| EP-0479601-A2 | Piperidine derivatives and their use as antiarrhythmic agents | Ajinomoto Co., Inc. (JP) | 1992-04-08 | — | — | EP | disclosed |