Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESRRA | P11474 | 2/20 | 0.35 |
| ▸ | GPR139 | Q6DWJ6 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CTSA | P10619 | 1/20 | 0.33 |
| ▸ | NNMT | P40261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10856471 | 0.76 | — | — | |
| SCHEMBL11782841 | 0.70 | KMT2A (0.46) | ESRRAKDM4EALDH1A1HPGD | |
| SCHEMBL15767066 | 0.68 | SUV39H2 (0.32) | GPR139KDM4EALDH1A1 | |
| SCHEMBL10304878 | 0.63 | BRPF1 (0.43) | KDM4EALDH1A1HPGD | |
| SCHEMBL8291097 | 0.63 | ALDH1A1 (0.57) | KDM4EALDH1A1HPGD | |
| SCHEMBL16592837 | 0.61 | IRAK4 (0.44) | KDM4EALDH1A1HPGD | |
| SCHEMBL28541918 | 0.61 | MAPT (0.53) | KDM4EALDH1A1HPGD | |
| SCHEMBL10861325 | 0.60 | — | — | |
| SCHEMBL8880159 | 0.60 | KDM4E (0.42) | KDM4EALDH1A1HPGD | |
| SCHEMBL12447021 | 0.59 | ALDH1A1 (0.39) | KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0104104-A1 | Imidazo(1,2-a)pyrimidines and their salts, process and intermediates for their preparation, their use as medicaments and compositions containing them | ROUSSEL-UCLAF (FR) | 1984-03-28 | — | — | EP | claimed |