SCHEMBL7309655

SCHEMBL7309655

CCCCCCCCCCCCC(C#N)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 2/20 0.41
KCNH2 Q12809 2/20 0.41
CSNK1E P49674 1/20 0.41
CCR1 P32246 1/20 0.40
ALDH1A1 P00352 1/20 0.40
OPRM1 P35372 2/20 0.40
OPRD1 P41143 2/20 0.40
OPRK1 P41145 2/20 0.40
OPRL1 P41146 2/20 0.40
NAAA Q02083 2/20 0.40
SIGMAR1 Q99720 1/20 0.40
TRPA1 O75762 1/20 0.38
TSHR P16473 1/20 0.38
HRH1 P35367 1/20 0.38
ASAH1 Q13510 1/20 0.38
PRSS1 P07477 1/20 0.38
PRSS2 P07478 1/20 0.38
PRSS3 P35030 1/20 0.38
CYP19A1 P11511 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7754790 1.00 HTR2A (0.41) HTR2AKCNH2CSNK1ECCR1ALDH1A1
SCHEMBL28686925 1.00 HTR2A (0.41) HTR2AKCNH2CSNK1ECCR1ALDH1A1
SCHEMBL28978060 1.00 HTR2A (0.41) HTR2AKCNH2CSNK1ECCR1ALDH1A1
SCHEMBL1310360 0.98 CCR1 (0.41) HTR2AKCNH2CSNK1ECCR1ALDH1A1
SCHEMBL1445763 0.93 CCR1 (0.42) HTR2AKCNH2CCR1ALDH1A1OPRM1
SCHEMBL953748 0.85 TRPA1 (0.43) HTR2ACCR1ALDH1A1SIGMAR1TRPA1
SCHEMBL7361321 0.85 SIGMAR1 (0.44) HTR2AKCNH2CCR1OPRM1OPRD1
SCHEMBL9447543 0.84 HTT (0.38) KCNH2CCR1ALDH1A1CYP19A1
SCHEMBL11151613 0.84 CCR1 (0.41) HTR2ACCR1ALDH1A1SIGMAR1TRPA1
SCHEMBL11856682 0.83 CCR1 (0.43) CCR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102165957-B Synergic sterilizing composite containing fenbuconazole and triazole compound SHAANXI MEIBANG PESTICIDES CO 2014-03-05 CN disclosed
CN-102177899-A Antibacterial composition containing fenbuconazole and triazole compound SHAANXI MEIBANG PESTICIDE CO 2011-09-14 CN disclosed
CN-102165957-A Synergic sterilizing composite containing fenbuconazole and triazole compound SHAANXI MEIBANG PESTICIDE CO 2011-08-31 CN disclosed
US-4438131-A CARDIOVASCULAR DISORDERS BASF AKTIENGESELLSCHAFT (DE) 1984-03-20 US disclosed
EP-0064158-A1 Omega-cyano-1, omega-diphenyl azalcane derivatives, their preparation and pharmaceutical preparations containing them BASF Aktiengesellschaft (DE) 1982-11-10 EP disclosed