Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HPD | P32754 | 2/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7319899 | 0.87 | KDM4E (0.31) | KDM4ECYP2D6CYP2C19 | |
| SCHEMBL7306837 | 0.86 | KDM4E (0.30) | KDM4E | |
| SCHEMBL7316139 | 0.83 | ALDH1A1 (0.31) | KDM4EALDH1A1LMNAHTTPOLB | |
| SCHEMBL7314467 | 0.80 | ALDH1A1 (0.31) | KDM4EALDH1A1LMNAHTT | |
| SCHEMBL7310854 | 0.79 | ALDH1A1 (0.31) | KDM4EALDH1A1LMNAHTT | |
| SCHEMBL7309666 | 0.73 | KDM4E (0.38) | KDM4EKMT2AMAPTALDH1A1LMNA | |
| SCHEMBL10376949 | 0.73 | ALDH1A1 (0.34) | KDM4EMAPTALDH1A1LMNACYP2D6 | |
| SCHEMBL10376145 | 0.70 | POLB (0.31) | KDM4EKMT2AALDH1A1LMNAHTT | |
| SCHEMBL10374500 | 0.68 | PDE3B (0.51) | — | |
| SCHEMBL11114380 | 0.68 | ALDH1A1 (0.34) | KDM4EKMT2AMAPTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |