Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7311157 | 0.95 | ATM (0.41) | ALDH1A1MAPK1MAPTMEN1KMT2A | |
| SCHEMBL7314872 | 0.87 | NPC1 (0.40) | ALDH1A1MAPK1MAPTMEN1KMT2A | |
| SCHEMBL7321016 | 0.85 | ALDH1A1 (0.38) | ALDH1A1MAPK1MAPTMEN1KMT2A | |
| SCHEMBL7316814 | 0.82 | NPC1 (0.42) | ALDH1A1MAPK1MAPTMEN1KMT2A | |
| SCHEMBL7309728 | 0.82 | MAPK1 (0.38) | ALDH1A1MAPK1MAPTMEN1KMT2A | |
| SCHEMBL7318298 | 0.82 | KDM4E (0.45) | ALDH1A1MAPK1MAPTMEN1KMT2A | |
| SCHEMBL7314547 | 0.81 | KDM4E (0.46) | ALDH1A1MAPK1MAPTMEN1KMT2A | |
| SCHEMBL7311396 | 0.80 | ATM (0.41) | ALDH1A1MAPK1MAPTMEN1KMT2A | |
| SCHEMBL7309722 | 0.78 | SIRT3 (0.44) | ALDH1A1MAPK1MAPTMEN1KMT2A | |
| SCHEMBL7319259 | 0.75 | ATM (0.38) | ALDH1A1MAPK1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |