Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 6/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7314882 | 0.87 | NPC1 (0.41) | MAPK1MAPTALDH1A1GAAMEN1 | |
| SCHEMBL7321025 | 0.85 | ALDH1A1 (0.39) | MAPK1MAPTALDH1A1GAAMEN1 | |
| SCHEMBL7309718 | 0.82 | ALDH1A1 (0.38) | MAPK1MAPTALDH1A1GAAMEN1 | |
| SCHEMBL7318308 | 0.81 | NPC1 (0.39) | MAPTALDH1A1GAAMEN1KMT2A | |
| SCHEMBL7314556 | 0.81 | SMN1; SMN2 (0.40) | MAPK1MAPTALDH1A1GAAMEN1 | |
| SCHEMBL7316028 | 0.79 | NPC1 (0.42) | MAPTALDH1A1GAAKMT2ALMNA | |
| SCHEMBL7311157 | 0.77 | ATM (0.41) | MAPK1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL7309722 | 0.74 | SIRT3 (0.44) | MAPK1MAPTALDH1A1GAAMEN1 | |
| SCHEMBL7312257 | 0.73 | ALDH1A1 (0.37) | MAPTALDH1A1GAAMEN1KMT2A | |
| SCHEMBL7316959 | 0.69 | ALDH1A1 (0.35) | MAPK1MAPTALDH1A1GAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |