Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 6/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | STAT3 | P40763 | 1/20 | 0.50 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20335080 | 0.81 | FPR2 (0.74) | FPR2MEN1KMT2ACYP2C9CYP2C19 | |
| SCHEMBL20335078 | 0.81 | FPR2 (0.74) | FPR2MEN1KMT2ACYP2C9CYP2C19 | |
| SCHEMBL7304292 | 0.81 | KMT2A (0.57) | MEN1KMT2ACYP2C9CYP2C19MAPT | |
| SCHEMBL10795899 | 0.81 | FPR2 (0.73) | FPR2MEN1KMT2ACYP2C9CYP2C19 | |
| SCHEMBL20335126 | 0.81 | FPR2 (0.73) | FPR2MEN1KMT2ACYP2C9CYP2C19 | |
| SCHEMBL16024649 | 0.80 | FPR2 (0.72) | FPR2MEN1KMT2ACYP2C9CYP2C19 | |
| SCHEMBL22506222 | 0.80 | FPR2 (1.00) | FPR2MEN1KMT2AMAPTGAA | |
| SCHEMBL16009024 | 0.80 | FPR2 (1.00) | FPR2MEN1KMT2AMAPTGAA | |
| SCHEMBL4112603 | 0.76 | MEN1 (0.75) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL4110308 | 0.75 | MAPT (0.68) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0494071-B1 | Trifluoromethylketone tripeptide derivatives | FUJISAWA PHARMACEUTICAL CO (JP) | 1997-04-16 | — | — | EP | disclosed |
| US-5430025-A | Elastase-inhibiting peptides bearing a C-terminal trifluoromethylketone moiety | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-07-04 | — | — | US | disclosed |
| US-5296591-A | Enzyme inhibitors | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-03-22 | — | — | US | disclosed |
| EP-0494071-A2 | Trifluoromethylketone tripeptide derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-07-08 | — | — | EP | disclosed |