Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 4/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | TRPM5 | Q9NZQ8 | 3/20 | 0.37 |
| ▸ | TRPM4 | Q8TD43 | 2/20 | 0.37 |
| ▸ | KMO | O15229 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MYC | P01106 | 1/20 | 0.34 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11184701 | 0.80 | EDNRB (0.41) | MDM2ATMTRPM5TRPM4KMO | |
| SCHEMBL7309916 | 0.73 | KMT2A (0.39) | ATMTRPM5MEN1KMT2AHTT | |
| SCHEMBL7317502 | 0.73 | MEN1 (0.38) | MDM2ATMTRPM5TRPM4MEN1 | |
| SCHEMBL7315680 | 0.71 | PTAFR (0.47) | MDM2MEN1KMT2A | |
| SCHEMBL11287985 | 0.71 | TRPM5 (0.42) | ATMTRPM5TRPM4MEN1KMT2A | |
| SCHEMBL11284457 | 0.71 | TRPM5 (0.42) | ATMTRPM5TRPM4MEN1KMT2A | |
| SCHEMBL11281221 | 0.71 | TRPM5 (0.42) | ATMTRPM5TRPM4MEN1KMT2A | |
| SCHEMBL7384311 | 0.70 | OPRK1 (0.49) | MDM2MEN1KMT2AMAPTPOLB | |
| SCHEMBL7317722 | 0.68 | MEN1 (0.39) | ATMTRPM5MEN1KMT2AMAPT | |
| SCHEMBL11434287 | 0.68 | BRD4 (0.42) | TRPM5TRPM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4440685-A | MUSCLE RELAXANTS, SEDATIVES, ANTICONVULSANTS | HOFFMANN-LA ROCHE INC. (US) | 1984-04-03 | — | — | US | claimed |