Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.52 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | ADCY6 | O43306 | 1/20 | 0.42 |
| ▸ | ADCY3 | O60266 | 1/20 | 0.42 |
| ▸ | ADCY9 | O60503 | 1/20 | 0.42 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.42 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.42 |
| ▸ | GCGR | P47871 | 1/20 | 0.42 |
| ▸ | ADCY7 | P51828 | 1/20 | 0.42 |
| ▸ | ADCY2 | Q08462 | 1/20 | 0.42 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.42 |
| ▸ | ADCY4 | Q8NFM4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7322138 | 0.98 | MMEL1 (0.52) | MMEL1SRCADCY6ADCY3ADCY9 | |
| SCHEMBL7316584 | 0.95 | MMEL1 (0.57) | MMEL1 | |
| SCHEMBL7310423 | 0.95 | MMEL1 (0.57) | MMEL1 | |
| SCHEMBL7314722 | 0.91 | MMEL1 (0.53) | MMEL1ADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL7313027 | 0.90 | MMEL1 (0.52) | MMEL1 | |
| SCHEMBL7317532 | 0.90 | MMEL1 (0.52) | MMEL1SRC | |
| SCHEMBL7318630 | 0.89 | MMEL1 (0.53) | MMEL1SRCADCY6ADCY3ADCY9 | |
| SCHEMBL7322636 | 0.89 | SRC (0.49) | MMEL1SRC | |
| SCHEMBL7313706 | 0.89 | MMEL1 (0.50) | MMEL1SRC | |
| SCHEMBL7341079 | 0.89 | MMEL1 (0.50) | MMEL1SRCADCY6ADCY3ADCY9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0511940-A2 | Phosphono/biaryl substituted dipeptide derivatives | CIBA-GEIGY AG (CH) | 1992-11-04 | — | — | EP | claimed |
| EP-0592367-A2 | Phosphono/biaryl substituted dipeptide derivatives | CIBA-GEIGY AG (CH) | 1994-04-13 | — | — | EP | disclosed |
| US-5294632-A | Diuretics and vasorelaxants | CIBA-GEIGY CORPORATION (US) | 1994-03-15 | — | — | US | disclosed |
| EP-0511940-A2 | Phosphono/biaryl substituted dipeptide derivatives | CIBA-GEIGY AG (CH) | 1992-11-04 | — | — | EP | disclosed |
| US-5155100-A | Treating cardiovascular disorders in mammals | CIBA-GEIGY CORPORATION (US) | 1992-10-13 | — | — | US | disclosed |