Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.41 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7313862 | 0.99 | PDE3B (0.40) | PDE3BPDE3AHSD17B10ALDH1A1HSPA1A | |
| SCHEMBL8258749 | 0.82 | PDE3B (0.44) | PDE3BPDE3AALDH1A1EGFRPDGFRA | |
| Hydrochloric Acid SCHEMBL7307891 | 0.81 | MAPT (0.36) | PDE3BPDE3AHSD17B10ALDH1A1HSPA1A | |
| SCHEMBL7318714 | 0.79 | AHR (0.38) | GAA | |
| SCHEMBL7044783 | 0.79 | GAA (0.55) | PDE3BPDE3AHSD17B10ALDH1A1HSPA1A | |
| SCHEMBL7037302 | 0.79 | GAA (0.55) | PDE3BPDE3AHSD17B10ALDH1A1HSPA1A | |
| SCHEMBL4365304 | 0.79 | GAA (0.55) | PDE3BPDE3AHSD17B10ALDH1A1HSPA1A | |
| Hydrochloric Acid SCHEMBL10910510 | 0.78 | GAA (0.54) | PDE3BPDE3AHSD17B10ALDH1A1HSPA1A | |
| Hydrochloric Acid SCHEMBL7323833 | 0.78 | AHR (0.37) | GAA | |
| SCHEMBL7286562 | 0.75 | ALDH1A1 (0.44) | PDE3BPDE3AHSD17B10ALDH1A1HSPA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0050850-A1 | 1-Carboxyalkanoylindolin-2-carboxylic acids and derivatives thereof, processes for their preparation, and pharmaceutical compositions containing these compounds | CIBA-GEIGY AG (CH) | 1982-05-05 | — | — | EP | disclosed |