Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 2/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SNCA | P37840 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | BCL2 | P10415 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13937919 | 0.88 | HTR5A (0.44) | PDE3BPDE3ADRD2DRD3CHRNB2 | |
| SCHEMBL7309997 | 0.82 | PDE3B (0.41) | PDE3BPDE3ADRD2DRD3EGFR | |
| SCHEMBL11087883 | 0.81 | PDE3B (0.45) | PDE3BPDE3ADRD2DRD3EGFR | |
| Hydrochloric Acid SCHEMBL7313862 | 0.81 | PDE3B (0.40) | PDE3BPDE3AEGFRPDGFRAKDR | |
| SCHEMBL7297564 | 0.76 | PDE3B (0.41) | PDE3BPDE3ADRD2DRD3EGFR | |
| SCHEMBL8399480 | 0.76 | PDE3B (0.44) | PDE3BPDE3ADRD2DRD3EGFR | |
| SCHEMBL7297572 | 0.76 | PDE3B (0.41) | PDE3BPDE3ADRD2DRD3EGFR | |
| SCHEMBL7037302 | 0.74 | GAA (0.55) | PDE3BPDE3AALDH1A1GAAACHE | |
| SCHEMBL11699617 | 0.74 | SLC6A2 (0.44) | GAAMAOBCYP19A1 | |
| SCHEMBL4365304 | 0.74 | GAA (0.55) | PDE3BPDE3AALDH1A1GAAACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006102760-A1 | INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE INC. (CA) | 2006-10-05 | — | — | WO | disclosed |