Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | UTS2R | Q9UKP6 | 5/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KLK7 | P49862 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7310744 | 0.87 | HPGD (0.49) | MAPTFOLH1HPGDALOX15CYP1A2 | |
| SCHEMBL16742520 | 0.86 | FPR2 (0.57) | FOLH1HPGDCYP1A2CYP2D6CYP2C9 | |
| SCHEMBL16742517 | 0.86 | FPR2 (0.57) | FOLH1HPGDCYP1A2CYP2D6CYP2C9 | |
| SCHEMBL7309151 | 0.85 | HTT (0.53) | MAPTHPGDEPHX2SMN1; SMN2ALDH1A1 | |
| SCHEMBL7299800 | 0.84 | HPGD (0.67) | MAPTHPGDALOX15CYP1A2CYP2C9 | |
| SCHEMBL1406054 | 0.83 | MAPT (0.52) | MAPTUTS2REPHX2CYP1A2CYP2D6 | |
| SCHEMBL4472986 | 0.83 | MAPT (0.52) | MAPTUTS2REPHX2CYP1A2CYP2D6 | |
| SCHEMBL8320803 | 0.83 | MAPT (0.52) | MAPTUTS2REPHX2CYP1A2CYP2D6 | |
| SCHEMBL19563374 | 0.82 | UTS2R (0.47) | UTS2REPHX2NPC1RAB9AL3MBTL1 | |
| SCHEMBL16742479 | 0.82 | UTS2R (0.47) | UTS2REPHX2NPC1RAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520336-A2 | Aldehyde derivatives and their use as calpain inhibitors | FUJIREBIO Inc. (JP) | 1992-12-30 | — | — | EP | disclosed |