Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | GRN | P28799 | 1/20 | 0.46 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | GRM5 | P41594 | 1/20 | 0.44 |
| ▸ | FPR2 | P25090 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7310030 | 0.85 | MAPT (0.56) | SMN1; SMN2KMT2AMAPTCYP3A4EPHX2 | |
| SCHEMBL7299800 | 0.83 | HPGD (0.67) | HTTLMNASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL7302122 | 0.81 | RAB9A (0.56) | HTTLMNASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL7310744 | 0.80 | HPGD (0.49) | HTTLMNASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL10608407 | 0.80 | HTT (0.71) | HTTLMNASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL16742520 | 0.80 | FPR2 (0.57) | SMN1; SMN2KMT2AMEN1HPGDFPR2 | |
| SCHEMBL16742517 | 0.80 | FPR2 (0.57) | SMN1; SMN2KMT2AMEN1HPGDFPR2 | |
| SCHEMBL8089265 | 0.77 | ANPEP (0.52) | HTTSMN1; SMN2KMT2AMEN1MAPT | |
| SCHEMBL7305243 | 0.77 | ANPEP (0.52) | HTTSMN1; SMN2KMT2AMEN1MAPT | |
| SCHEMBL19563374 | 0.76 | UTS2R (0.47) | HTTLMNAKMT2AMEN1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520336-A2 | Aldehyde derivatives and their use as calpain inhibitors | FUJIREBIO Inc. (JP) | 1992-12-30 | — | — | EP | disclosed |