⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20565668 | 0.72 | — | — | |
| SCHEMBL15559782 | 0.70 | CA2 (0.33) | — | |
| SCHEMBL1286372 | 0.69 | — | — | |
| SCHEMBL815357 | 0.69 | — | — | |
| SCHEMBL11410665 | 0.67 | — | — | |
| SCHEMBL10854919 | 0.67 | — | — | |
| SCHEMBL6762084 | 0.67 | — | — | |
| SCHEMBL3320964 | 0.67 | — | — | |
| SCHEMBL1059082 | 0.67 | — | — | |
| SCHEMBL491153 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 277 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3191482-B1 | 1,2,3-THIADIAZOL-5YL-UREA DERIVATIVES, USE THEREOF FOR REGULATING PLANT SENESCENCE AND PREPARATIONS CONTAINING THESE DERIVATIVES | USTAV EXPERIMENTALNI BOTANIKY AV CR V V I (CZ) | 2019-03-27 | — | — | EP | claimed |
| EP-3407361-A1 | REDOX MELTS FORMED BY COPPER (I)/(II) COMPLEXES AS CHARGE TRANSFER AND CHARGE STORAGE MATERIALS | Ecole Polytechnique Fédérale de Lausanne (EPFL) (CH) | 2018-11-28 | — | — | EP | claimed |
| US-8063151-B2 | Methods for manufacturing copolymers having 1-methyl-2-methoxyethyl moieties and use of same | ABBOTT LABORATORIES (US) | 2011-11-22 | — | — | US | claimed |
| CN-1031992-C | Quinone derivatives and pharmacological use | EISAI CO LTD (JP) | 1996-06-12 | — | — | CN | claimed |
| US-5496499-A | Biphenylethanes and liquid-crystalline phase | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1996-03-05 | — | — | US | claimed |
| CN-118317774-A | Pharmaceutical compositions comprising quinazoline compounds | 安斯泰来制药株式会社 | 2024-07-09 | — | — | CN | disclosed |
| US-20240182483-A1 | QUINAZOLINE COMPOUND FOR INDUCING DEGRADATION OF G12D MUTANT KRAS PROTEIN | ASTELLAS PHARMA INC. (JP) | 2024-06-06 | — | — | US | disclosed |
| WO-2024034657-A1 | PHARMACEUTICAL COMPOSITION COMPRISING HETEROCYCLIC COMPOUND | アステラス製薬株式会社 | 2024-02-15 | — | — | WO | disclosed |
| WO-2024034593-A1 | HETEROCYCLIC COMPOUND FOR INDUCING DEGRADATION OF G12V MUTANT KRAS PROTEIN | アステラス製薬株式会社 | 2024-02-15 | — | — | WO | disclosed |
| WO-2024034123-A1 | PHARMACEUTICAL COMPOSITION CONTAINING HETEROCYCLIC COMPOUND | アステラス製薬株式会社 | 2024-02-15 | — | — | WO | disclosed |
| WO-2024034591-A1 | HETEROCYCLIC COMPOUND FOR INHIBITING AND/OR INDUCING DEGRADATION OF KRAS PROTEIN | アステラス製薬株式会社 | 2024-02-15 | — | — | WO | disclosed |
| WO-2024029613-A1 | HETEROCYCLIC COMPOUND FOR INDUCING DEGRADATION OF MUTANT KRAS PROTEIN | アステラス製薬株式会社 | 2024-02-08 | — | — | WO | disclosed |
| EP-0161211-A1 | N-heterocyclosulfonyl-N'-pyrimidinyl and -triazinyl ureas | CIBA-GEIGY AG (CH) | 1985-11-13 | — | — | EP | disclosed |
| US-4477447-A | ANTIBIOTIC, BACTERICIDE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-10-16 | — | — | US | disclosed |
| US-4456471-A | PREEMERGENCE HERBICIDE FOR GRASSES | CHEVRON RESEARCH COMPANY (US) | 1984-06-26 | — | — | US | disclosed |
| US-4448776-A | Method of using certain substituted aliphatic secondary amines or their salts for easing breathing | BUCHER KARL (CH) | 1984-05-15 | — | — | US | disclosed |
| US-4348222-A | Herbicidal N-haloacetyl-2-alkyl-6-acylanilines | CHEVRON RESEARCH COMPANY (US) | 1982-09-07 | — | — | US | disclosed |
| EP-0058373-A1 | Substituted aliphatic secondary amines and their salts, pharmaceutical compositions containing them and their use | CIBA-GEIGY AG (CH) | 1982-08-25 | — | — | EP | disclosed |
| EP-0046451-A2 | Diaryl-imidazole compounds, methods for their preparation, pharmaceutical drugs containing them and their use | CIBA-GEIGY AG (CH) | 1982-02-24 | — | — | EP | disclosed |
| US-4244730-A | Herbicidal N-haloacetyl-2-alkyl-6-acylanilines | CHEVRON RESEARCH COMPANY (US) | 1981-01-13 | — | — | US | disclosed |