Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 8/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 8/20 | 0.45 |
| ▸ | PDE4C | Q08493 | 8/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 8/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | CCKBR | P32239 | 2/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.34 |
| ▸ | MET | P08581 | 1/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7311023 | 0.91 | PDE4A (0.52) | PDE4APDE4BPDE4CPDE4DCNR1 | |
| SCHEMBL7312716 | 0.91 | PDE4A (0.48) | PDE4APDE4BPDE4CPDE4DCNR1 | |
| SCHEMBL7314040 | 0.90 | LMNA (0.41) | PDE4APDE4BPDE4CPDE4DCNR1 | |
| SCHEMBL7307091 | 0.89 | PDE4A (0.47) | PDE4APDE4BPDE4CPDE4DCNR1 | |
| SCHEMBL7316981 | 0.87 | PDE4A (0.43) | PDE4APDE4BPDE4CPDE4DCNR1 | |
| SCHEMBL7317319 | 0.85 | PDE4A (0.48) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7310209 | 0.84 | PDE4A (0.39) | PDE4APDE4BPDE4CPDE4DITGB3 | |
| SCHEMBL7316041 | 0.84 | PDE4A (0.40) | PDE4APDE4BPDE4CPDE4DCNR1 | |
| SCHEMBL7320570 | 0.82 | PDE4A (0.41) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL7318905 | 0.82 | PDE4A (0.44) | PDE4APDE4BPDE4CPDE4DCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4739056-A | ENZYME INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1988-04-19 | — | — | US | disclosed |