SCHEMBL7310233

SCHEMBL7310233

O=Cc1cc(OCCCCC(=O)O)cc(Cl)c1[N+](=O)[O-]

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 2/20 0.40
PPARA Q07869 5/20 0.39
ALB P02768 1/20 0.38
MCL1 Q07820 1/20 0.38
FFAR1 O14842 3/20 0.38
PPARG P37231 3/20 0.38
PPARD Q03181 1/20 0.38
S1PR1 P21453 1/20 0.38
S1PR3 Q99500 1/20 0.38
GPR17 Q13304 3/20 0.36
FFAR4 Q5NUL3 2/20 0.36
SERPINE1 P05121 1/20 0.36
LTB4R Q15722 1/20 0.35
CYP2C9 P11712 1/20 0.34
SCN5A Q14524 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7309684 0.99 PDK2 (0.39) PDK2PPARAALBMCL1FFAR1
SCHEMBL7318223 0.96 MCL1 (0.39) PDK2PPARAMCL1FFAR1PPARG
Hydrochloric Acid SCHEMBL7307876 0.95 PDK2 (0.38) PDK2PPARAMCL1FFAR1PPARG
SCHEMBL7309678 0.90 THRB (0.34) PDK2MCL1S1PR1S1PR3
SCHEMBL7307867 0.86 MAPT (0.34) MCL1S1PR1S1PR3
SCHEMBL7314738 0.85 FBP1 (0.40) PDK2CYP2C9
SCHEMBL7308480 0.85 MCL1 (0.40) MCL1
SCHEMBL7311187 0.84 MCL1 (0.43) PPARAALBMCL1FFAR1PPARG
Hydrochloric Acid SCHEMBL7318385 0.84 MCL1 (0.40) MCL1
Hydrochloric Acid SCHEMBL7305466 0.83 MCL1 (0.42) PPARAALBMCL1FFAR1PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4670434-A ANTICOAGULANT, INOTROPIC AGENT SYNTEX (U.S.A.) INC. (US) 1987-06-02 US disclosed