Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.49 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.43 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | PAM | P19021 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7310294 | 1.00 | HTR2A (0.49) | HTR2AGRIK1GRIK2IDO1PAM | |
| SCHEMBL19143267 | 0.81 | HTR2A (0.61) | HTR2AGRIK1GRIK2IDO1PAM | |
| SCHEMBL7310968 | 0.81 | HTR2A (0.61) | HTR2AGRIK1GRIK2IDO1PAM | |
| SCHEMBL7310970 | 0.81 | HTR2A (0.61) | HTR2AGRIK1GRIK2IDO1PAM | |
| Hydrochloric Acid SCHEMBL28741289 | 0.80 | HTR2A (0.59) | HTR2AGRIK1GRIK2IDO1PAM | |
| SCHEMBL11155036 | 0.79 | HTR2A (0.46) | HTR2AIDO1SIGMAR1 | |
| SCHEMBL20286655 | 0.77 | PAM (0.48) | HTR2AGRIK1GRIK2IDO1PAM | |
| SCHEMBL9696384 | 0.76 | GRIK1 (0.42) | HTR2AGRIK1GRIK2IDO1PAM | |
| SCHEMBL1301627 | 0.74 | PAM (0.54) | HTR2AIDO1PAMSIGMAR1MAOB | |
| SCHEMBL1301624 | 0.74 | PAM (0.54) | HTR2AIDO1PAMSIGMAR1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520336-A2 | Aldehyde derivatives and their use as calpain inhibitors | FUJIREBIO Inc. (JP) | 1992-12-30 | — | — | EP | disclosed |