Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 5/20 | 0.42 |
| ▸ | GRIK2 | Q13002 | 4/20 | 0.42 |
| ▸ | PAM | P19021 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 3/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.35 |
| ▸ | CTSC | P53634 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7310290 | 0.76 | HTR2A (0.49) | GRIK1GRIK2PAMHTR2AMAOB | |
| SCHEMBL7310294 | 0.76 | HTR2A (0.49) | GRIK1GRIK2PAMHTR2AMAOB | |
| SCHEMBL27965598 | 0.72 | PAM (0.55) | GRIK1GRIK2PAMHTR2AMAOB | |
| SCHEMBL27978309 | 0.68 | PAM (0.50) | GRIK1GRIK2PAMHTR2AMAOB | |
| SCHEMBL20286655 | 0.68 | PAM (0.48) | GRIK1GRIK2PAMHTR2AMAOB | |
| SCHEMBL10453266 | 0.67 | PAM (0.53) | PAMMAOBHDAC3HDAC4HDAC1 | |
| SCHEMBL27792638 | 0.67 | HTR2A (0.46) | GRIK1GRIK2PAMHTR2AHDAC3 | |
| SCHEMBL3758840 | 0.66 | PAM (0.47) | GRIK1GRIK2PAMHTR2AMAOB | |
| SCHEMBL1301627 | 0.66 | PAM (0.54) | PAMHTR2AMAOBHDAC3HDAC4 | |
| SCHEMBL1301624 | 0.66 | PAM (0.54) | PAMHTR2AMAOBHDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5110886-A | Cationic polymer having at least one heterocyclic ring | NIPPON ZEON CO., LTD. (JP) | 1992-05-05 | — | — | US | disclosed |