Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 3/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | GRM8 | O00222 | 1/20 | 0.45 |
| ▸ | GRM6 | O15303 | 1/20 | 0.45 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KMO | O15229 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL925746 | 0.82 | TSHR (0.54) | F2TSHRMAOBMAOACYP2D6 | |
| SCHEMBL9506155 | 0.81 | TSHR (0.50) | TSHRMAOBMAOACYP2D6CYP2C9 | |
| SCHEMBL926393 | 0.80 | TSHR (0.51) | F2TSHRMAOBMAOACYP2D6 | |
| SCHEMBL17678491 | 0.80 | TSHR (0.51) | F2TSHRMAOBMAOACYP2D6 | |
| SCHEMBL16836911 | 0.79 | TSHR (0.54) | F2TSHRGRM8GRM6GRM4 | |
| SCHEMBL6191530 | 0.79 | TSHR (0.54) | F2TSHRGRM8GRM6GRM4 | |
| SCHEMBL6188426 | 0.79 | TSHR (0.54) | F2TSHRGRM8GRM6GRM4 | |
| SCHEMBL30537970 | 0.79 | TSHR (0.54) | F2TSHRGRM8GRM6GRM4 | |
| SCHEMBL18714233 | 0.79 | TSHR (0.57) | F2TSHRMAOBMAOAALDH1A1 | |
| SCHEMBL1767329 | 0.79 | TSHR (0.65) | F2TSHRMAOBMAOACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520336-A2 | Aldehyde derivatives and their use as calpain inhibitors | FUJIREBIO Inc. (JP) | 1992-12-30 | — | — | EP | disclosed |