Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | METAP2 | P50579 | 1/20 | 0.47 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | TSPO | P30536 | 1/20 | 0.45 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CDK4 | P11802 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CTSG | P08311 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7272298 | 1.00 | NPC1 (0.48) | NPC1RAB9AMETAP2HRH4KMT2A | |
| SCHEMBL10756689 | 0.86 | CTNNB1 (0.50) | METAP2HRH4CTNNB1TDP1CYP1A2 | |
| SCHEMBL10477863 | 0.85 | CTNNB1 (0.45) | METAP2HRH4KMT2AMEN1CTNNB1 | |
| SCHEMBL7275603 | 0.83 | HRH4 (0.45) | METAP2HRH4KMT2ACTNNB1CYP1A2 | |
| SCHEMBL7274920 | 0.83 | CPA1 (0.60) | NPC1RAB9AKMT2AHPGDTDP1 | |
| SCHEMBL10477711 | 0.82 | MMP9 (0.42) | HRH4KMT2AMEN1CTNNB1TDP1 | |
| SCHEMBL7290086 | 0.81 | TSHR (0.48) | HRH4KMT2AMEN1CTNNB1TDP1 | |
| SCHEMBL10477663 | 0.81 | CYP1A2 (0.41) | HRH4KMT2AMEN1CTNNB1TDP1 | |
| SCHEMBL7429100 | 0.79 | CPA1 (0.57) | HRH4CTNNB1HPGDTDP1CYP1A2 | |
| SCHEMBL7352579 | 0.79 | CYP1A2 (0.65) | HRH4KMT2AMEN1CTNNB1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0274259-A2 | New renin-inhibitory oligopeptides, their preparaton and their use | Sankyo Company Limited (JP) | 1988-07-13 | — | — | EP | disclosed |