Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.43 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11095433 | 0.84 | AOC3 (0.44) | — | |
| SCHEMBL1337896 | 0.84 | HPGD (0.56) | HPGDKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL8086800 | 0.82 | TACR1 (0.41) | KMT2AMEN1TDP1 | |
| SCHEMBL8304511 | 0.80 | HPGD (0.59) | HPGDKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL900941 | 0.80 | HPGD (0.69) | HPGDKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL27598559 | 0.79 | HPGD (0.58) | HPGDKMT2AMEN1RAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL7452576 | 0.79 | HPGD (0.67) | HPGDKMT2AMEN1RAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL6503199 | 0.79 | HPGD (0.67) | HPGDKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL13995143 | 0.78 | HPGD (0.60) | HPGDKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL10423904 | 0.77 | AKT1 (0.41) | KMT2AMEN1CHRNB2CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041064-A2 | N-substituted alpha aminoacid amides as calcium channel modulators | ELI LILLY AND COMPANY LIMITED (GB) | 2000-10-04 | — | — | EP | disclosed |
| EP-0805147-A1 | Novel N-substituted alpha aminoacid amides as calcium channel modulators | LILLY INDUSTRIES LIMITED (GB) | 1997-11-05 | — | — | EP | disclosed |