Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | FNTA | P49354 | 4/20 | 0.39 |
| ▸ | FNTB | P49356 | 4/20 | 0.39 |
| ▸ | KLK7 | P49862 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.38 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.38 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10425083 | 0.85 | CTSK (0.44) | AKT1HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL1737432 | 0.84 | AKT1 (0.42) | AKT1ALDH1A1LMNAHSD17B10HDAC3 | |
| SCHEMBL1737441 | 0.82 | HDAC3 (0.42) | AKT1TSHRHDAC3HDAC1HDAC2 | |
| SCHEMBL10423913 | 0.79 | AKT1 (0.42) | AKT1MEN1ALDH1A1LMNAKMT2A | |
| SCHEMBL3819098 | 0.78 | AKT1 (0.52) | AKT1MEN1LMNAKMT2AHDAC3 | |
| SCHEMBL268899 | 0.78 | BCHE (0.43) | MEN1ALDH1A1KMT2A | |
| SCHEMBL7310455 | 0.77 | HPGD (0.52) | MEN1KMT2ACHRNB2CHRNB4CHRNA3 | |
| SCHEMBL10423905 | 0.77 | AKT1 (0.41) | AKT1MEN1ALDH1A1LMNATSHR | |
| SCHEMBL30744052 | 0.74 | CTSS (0.36) | ALDH1A1HSD17B10 | |
| SCHEMBL29147407 | 0.74 | CTSS (0.36) | ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4918105-A | Novel compounds with collagenase-inhibiting activity, a process for their preparation and pharmaceutical compositions in which these compounds are present | SA LABORATOIRE ROGER BELLON (FR) | 1990-04-17 | — | — | US | disclosed |