Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | BMP1 | P13497 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7310511 | 1.00 | ALDH1A1 (0.39) | ALDH1A1USP2MAPTHPGDCCNA2 | |
| SCHEMBL9555625 | 0.71 | HPGD (0.44) | ALDH1A1MAPTHPGDCCNA2CDK2 | |
| SCHEMBL7269236 | 0.70 | MAPT (0.41) | ALDH1A1MAPTHPGDMEN1KMT2A | |
| SCHEMBL7269246 | 0.70 | MAPT (0.41) | ALDH1A1MAPTHPGDMEN1KMT2A | |
| SCHEMBL7269517 | 0.69 | MEN1 (0.47) | ALDH1A1HPGDMEN1KMT2ANFE2L2 | |
| SCHEMBL15130391 | 0.66 | MAPT (0.41) | ALDH1A1USP2MAPTHPGD | |
| SCHEMBL9739839 | 0.65 | MAPT (0.37) | ALDH1A1USP2MAPTHPGD | |
| SCHEMBL7293215 | 0.65 | METAP1 (0.39) | ALDH1A1USP2HPGDMEN1KMT2A | |
| SCHEMBL7275541 | 0.65 | METAP1 (0.39) | ALDH1A1USP2HPGDMEN1KMT2A | |
| SCHEMBL9739846 | 0.65 | MAPT (0.37) | ALDH1A1USP2MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5459131-A | Renin inhibitors | AMERICAN CYANAMID COMPANY (US) | 1995-10-17 | — | — | US | disclosed |