Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7269236 | 1.00 | MAPT (0.41) | MAPTALOX5CYP2C19NPC1HTT | |
| SCHEMBL9442571 | 0.70 | — | — | |
| SCHEMBL7310511 | 0.70 | ALDH1A1 (0.39) | MAPTHPGDKMT2AMEN1ALDH1A1 | |
| SCHEMBL7310504 | 0.70 | ALDH1A1 (0.39) | MAPTHPGDKMT2AMEN1ALDH1A1 | |
| SCHEMBL7288246 | 0.68 | NPC1 (0.41) | MAPTNPC1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL7277251 | 0.68 | CHRM3 (0.38) | ALOX5CYP2C19NPC1RAB9AHPGD | |
| SCHEMBL27609999 | 0.68 | — | — | |
| SCHEMBL6609230 | 0.67 | MAPT (0.49) | MAPTALOX5CYP2C19NPC1RAB9A | |
| SCHEMBL17616424 | 0.67 | MAPT (0.49) | MAPTALOX5CYP2C19NPC1RAB9A | |
| SCHEMBL6627141 | 0.67 | MAPT (0.41) | MAPTALOX5CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0376040-A2 | N-phosphinyl di-and tripeptides as renin inhibitors | AMERICAN CYANAMID COMPANY (US) | 1990-07-04 | — | — | EP | disclosed |